Berberine is a dupe for metformin so I think it’s worth a shot. Metformin did not help my hair loss. It has helped with some reactive hypoglycemia. I tried Spiro! Zero Success it gave me the dread shed and I stopped it a few days ago after 6 …I had issues with low/zero appetite after starting Metformin. It got better gradually over a period of a few weeks and mostly went back to normal (except with fewer bouts of getting “hangry”/ravenous at the drop of a hat because my blood sugar had dropped). I have always had a fairly regulated appetite and am within a healthy BMI, but since my Dr put me on Metformin 6 weeks ago 2x 500mg, I've noticed quite a bit of weight gain in my legs and stomach and an increase in appetite overall : (. I was fine when it was 1x 500, but I have been gaining weight on the adjustment. Metformin doesn't really work that way, no. Metformin doesn't affects the food you eat. But, carbs aren't by definition bad. Whole plant based is a high carb diet, but often super successful in treating type 2 because of the type of food it focuses on.Metformin is the first medication almost everyone is put on because both IR and XR are super cheap. (I'm pretty sure XR costs more, but when I say "more" it's not that much more and still super cheap and definitely going to be less expensive than almost every other option.) Meformin is on the $4 list here in the US, and when I …Metformin doesnt decrease/increase insulin secretion. What it does is that it changes the response of tissues to insulin. Its an insulin sensitizer, meaning it will cause tissues to take up more glucose from blood. This is why its primary use is in type2 diabetes, these people have tissues that are "insulin resistant".healthyhealthhealth. • 5 yr. ago. I'm prediabetic but also on Metformin, and this is exactly how I've been feeling. I've been repulsed by all sorts of foods I used to enjoy and it's making me sad. Like I literally feel like I'm going to throw up with certain foods, and these are foods I would frequently eat. I thought I was the only one.For years mt HbA1c was ~ 7. My doc upped my metformin to 2G/daily. There was no change for 5 months then suddenly I lost 5 pounds ( I also changed my magnesium from citrate to gycinate) in one month without trying. I simply had no appetite. I cut back to 1500 mg metformin and the weight loss has continued about 1/4 pound/week.Increase your carb amount and try to eat those whole grains and vegetables. If you’re getting nausea, try an antihistamine to make sure it’s not a psychological kinda nausea, or lower your dosage of met and increase it slower. If you’re getting heart burn, reflux, etc, limit your citrus and acidic foods.That reason is likely b/c you have insulin resistance, which in turn is the underlying driver of the abnormal hormones that mess up cycling (in most cases of PCOS). Metformin helps treat the insulin resistance, which in turn helps normalize the abnormal hormones that cause the PCOS symptoms like abnormal cycling and lack of ovulation.It's been like that for about 18 years until I started Metformin and then it's just gone. Same with the acid reflux. It just got worse and worse and right before I started Metformin I'd wake up in the middle of the night with acid in my throat, and have to cough it out for like 30 minutes.Also PCOS and nondiabetic. The metformin is used to help regulate my hormones/cycles. It's been a godsend. Just make sure to know the signs and symptoms of hypoglycemia- the meds main job is to help lower blood sugar, if it drops too low it can be dangerous- I've had an easier time regulating it with the protein on keto. Metformin does have some adverse reactions. Diarrhea, flatulence, vomiting and nausea are common early reactions but no more usual in t1 than t2. Vitamin B12 deficiency is another one. Some very uncommon serious reactions are megaloblastic anemia, lactic acidosis, and hepatic toxicity. Metformin is an FDA-approved antidiabetic agent that manages high blood sugar levels in type 2 diabetes patients. It reduces glucose absorption from the intestines, …Rybelsus (pill form of ozempic) was absolutely terrible for my GI, so metformin was the next option. In a sufficient dose, it works really well!! If your hyperthyroid is not well controlled, you will get hypoglycemic on this medication. To manage that side effect, high protein-low (er) carb meals are your best option.I had issues with low/zero appetite after starting Metformin. It got better gradually over a period of a few weeks and mostly went back to normal (except with fewer bouts of getting “hangry”/ravenous at the drop of a hat because my blood sugar had dropped). I’ve heard of cases where people didn’t have a great reaction to metformin but saw better results on inositol. I’ve seen a few indicate the reverse. Plenty of people take the both together. I think it really varies from person to person but I read a recent meta-analysis that suggests that—at least in the short term—most people do well ... You just ask. You can start with your GP if you want or preferably if you can find a doctor that specializes is anti-aging start there. Doctors work for you, certainly don't be afraid to ask them direct questions. If they are uncomfortable prescribing the medication they'll let …Yes, it goes away almost completely. I’m on 2000 mg but it took almost a month to work up to that and a few month after that until the symptoms really eased up. Definitely go with the extended release formula and be patient. Good luck!! vivagypsy • 5 yr. ago. I had some GI upset last week which was week 1.Insulin kicks in when it starts approaching the max, and is absorbed well enough that the blood sugar gets used and goes back down. Pre-diabetes means your system is floating above that at like 100-120 or so. You are still utilizing insulin at …Things that control blood glucose via the same mechanisms will have similar hormesis-reducing effects. Although the AMPK activation from berberine is less than metformin. I personally use and really like berberine/DHB. Haven't noticed any decreases in endurance or lactate tolerance as is commonly reported with metformin.Patients treated with metformin lost on average 10-14 pounds (5.6% to 6.5% of body weight) compared to controls who gained 6-8 pounds during the same time period. What’s interesting is that the percentage of weight loss achieved in each individual was independent of age, sex, or BMI. This means that if you are …You do need to make lifestyle changes with or without metformin, but personally if I were you, I would take metformin because your insulin is through the roof. A healthy fasting insulin level is five or under. Your HOMA-IR is also very concerning; healthy is around one and over three is significant IR. So I think you just want to get things ...Apr 7, 2565 BE ... single. symptom., and the biggest being that it immediately fixed my amenorrhea. It lowered my sugar cravings (although the effect was stronger ...Metformin is an FDA-approved antidiabetic agent that manages high blood sugar levels in type 2 diabetes patients. It reduces glucose absorption from the intestines, …Metformin is designed to help the insulin you are currently making, absorb into the cells. Since Type 1s make ZERO insulin, it’s a waste to take it. Type 2 benefits as their body still produces insulin yet struggles to process it, enter Metformin.The other side effect is Metformin zombie, where one literally has no energy to do anything. Metformin is known to interfere with the B12 metabolism, but I don't know if that's the cause of the zombie effect. Yes, it has been reported that folks can take Metformin for awhile then the side effects return. Sil_Lavellan • 4 yr. ago.I take 1000 in the morning, and 1000 at night. The metformin half life in your bloodstream will remain the same no matter what time you take it. The difference will be how quickly and how completely your body absorbs it depending upon if your stomach is full or empty. According to the FDA, it is absorbed slightly faster and with slightly higher ...I was diagnosed with Type 2 diabetes three years ago, and was prescribed 1000 mg Metformin in the morning and night. My A1C number was 8.0 (fasting glucose 180) ...Medical Watch Digest for March 18 Metformin & Brain Development A popular drug, prescribed during pregnancy, could alter brain development in a growing baby. The …View community ranking In the Top 1% of largest communities on Reddit. Metformin and inhibition of gluconeogenesis: is it safe ... "This redox-dependent mechanism would also explain why metformin treatment is rarely associated with hypoglycemia given that gluconeogenesis will never be totally inhibited. "Not at all. I learned – as millions of people with type 2 diabetes have – that metformin doesn’t immediately lower your blood sugar. It can take four or five days to experience the full benefit, depending on your …Woah, metformin really works. (review) I've been recently diagnosed with lean PCOS and although I was technically "lean" as my BMI was 20 and I wasn't overweight, I've always been trying to lose weight. When my PCOS was rampant I was at 60kg, 168cm, and I felt bloated + had a face full of acne. (I'm asian so any excess weight goes straight to ...Apr 4, 2566 BE ... I also know diabetics who take metformin who were prescribed paxlovid, so there shouldn't be an issue, but check with your doctor to make sure ...Dec 25, 2565 BE ... Metformin is not like ozempic. It kinda works as a mild appetite suppressant. You have to put in the work to. Intermittent fasting n low calorie ... I have always had a fairly regulated appetite and am within a healthy BMI, but since my Dr put me on Metformin 6 weeks ago 2x 500mg, I've noticed quite a bit of weight gain in my legs and stomach and an increase in appetite overall : (. I was fine when it was 1x 500, but I have been gaining weight on the adjustment. Update: Got way worse this morning. Messaged the doc and he said to stop the glimepiride for now. New diagnosis, a little over a week in. My blood sugar is responding well to the metformin and glimepiride the doctor put me on, but I've noticed in the past couple days I've had a couple of 'black moods' - crying jags over silly things and the like - which usually …Like a couple of others mentioned, I was told to take a b-complex to offset what metformin depletes. In general, my fatigue before metformin was helped by taking a b12 supplement. I think is also depletes Vitamin D and sweet baby Jesus if my Vit D dips just a little bit I can't get out of bed and function as a human.Not at all. I learned – as millions of people with type 2 diabetes have – that metformin doesn’t immediately lower your blood sugar. It can take four or five days to experience the full benefit, depending on your …Like a couple of others mentioned, I was told to take a b-complex to offset what metformin depletes. In general, my fatigue before metformin was helped by taking a b12 supplement. I think is also depletes Vitamin D and sweet baby Jesus if my Vit D dips just a little bit I can't get out of bed and function as a human.In a short GnRH-antagonist protocol, metformin may reduce live birth rates, although we are uncertain about the effect of metformin on clinical pregnancy rate. Metformin may reduce the incidence of OHSS but may result in a higher incidence of side effects. We are uncertain of the effect of metformin on miscarriage rate per woman.Roger that, thanks, ChiknRice • 1 yr. ago. Improves insulin sensitivity and allows more energy going into cells for recovery, as well as more energy while working out as it allows for more proteins and carbs to enter the muscles. Good for bulking, and should add fullness.In July my a1c was 6.3% so i was diagnosed with prediabetes. My primary put me on extended release metformin at 500mg. I wasnt given any info about the drug or what I can do to prevent my diagnosis from progressing so I've had to rely on the internet (bad decision b/c every site says something completely different).reply. My doc suggested taking Metamucil two hours after the metformin to help with GI issues. It worked. Nah, I take it twice a day and it's fine. Been on it for 20+ years. No side effects that I’ve noticed. I went from 500 mg a day to 2000 mg in a day in one week. I am the opposite, now I can't go the bathroom.Insulin kicks in when it starts approaching the max, and is absorbed well enough that the blood sugar gets used and goes back down. Pre-diabetes means your system is floating above that at like 100-120 or so. You are still utilizing insulin at … The idea that it prevents ageing is a pretty cool idea. There's a few studies linking metformin with reduced cognitive impairment, reduced cancer risk and even reduced cellular aging. If you look at hyperinsulinemia and hyperglycemia in mammals, it has a link with increased aging, so the benefits do make sense. Alternative to metformin, preferably injectables. Prediabetic. Hi all, I was just diagnosed with pre-diabetes, and after a week on Metformin I can't tolerate it. The acid reflux was getting better until last night, when it came back with a vengeance, along with really bad nausea, stomach pain, a terrible metallic taste and a sore tongue (which ...Metformin has been the first-line treatment for type 2 diabetes mellitus for decades. The glucose-lowering effects of metformin were first discovered in the 1920s. 1 After …Keto, exercise, caloric restriction also pushes AMPK buttons, thus metformin might be redundant. Metformin inhibits both gluconeogenesis and ketogenesis, lowering both of your blood sugar and serum ketones. You might not notice the symptoms of hypoglycemia on keto, and it is unknown whether it is safe. 1. ZeroCarb. Lots of gas. Burping gas. Farting gas. Never smells of much. Gas when I eat. Gas when I don't eat. Gas. I'm on 2,000mg of the extended release per day. My only issues have been occasional diarrhea (it was very frequent when I first started), and sometimes if I let my stomach get too empty I'll feel nauseous. Keto on metformin. I’m currently taking metformin (blood glucose lowering drug) to counteract weight gain from an antipsychotic drug that caused me insulin resistance. I’m five days on strict keto and have been feeling a bit fatigued and nauseous, mostly after eating high fat foods. I previously thought this could be keto flu and ordered …I was diagnosed in November and started in late Nov/early Dec 2023 and am taking 1000mg daily. I’ve lost ~10lbs since I started. I have always been pretty active 3-5 days a week …Nov 27, 2563 BE ... I would trial it on a day you are ok to have stomach symptoms. If it works out, then it is fine. Metformin is absorbed with or without food. I’ve taken 500mg of Metformin and Mounjaro together the entire time I’ve been on it. (Now on the 12.5 dose.) I’ve steadily lost 1 to 2 lbs a week and my A1C, cholesterol and glucose numbers are awesome! The only side effect I’ve had has been heartburn - other than that, I feel great. I'm on metformin and Mounjaro. Rybelsus (pill form of ozempic) was absolutely terrible for my GI, so metformin was the next option. In a sufficient dose, it works really well!! If your hyperthyroid is not well controlled, you will get hypoglycemic on this medication. To manage that side effect, high protein-low (er) carb meals are your best option.Alcohol can drop your blood sugar, so keep an eye on it while drinking, and for several hours afterwards. 3. Meme-grabber • 2 yr. ago. I should share my story. A year ago I was tested. My a1c was 6.9. The doctor said you have type two diabetes. Prescribed me metformin and told me to lose weight.Using their understanding of clinical research, the authors recommended that the GLP-1 receptor agonists should be first-line therapy in type 2 diabetes. They invoke …Dec 10, 2566 BE ... I think the side effects of metformin are drastically overblown. A case of the minority of experiences having a very loud voice. Other than the ...Update: Got way worse this morning. Messaged the doc and he said to stop the glimepiride for now. New diagnosis, a little over a week in. My blood sugar is responding well to the metformin and glimepiride the doctor put me on, but I've noticed in the past couple days I've had a couple of 'black moods' - crying jags over silly things and the like - which usually …Also PCOS and nondiabetic. The metformin is used to help regulate my hormones/cycles. It's been a godsend. Just make sure to know the signs and symptoms of hypoglycemia- the meds main job is to help lower blood sugar, if it drops too low it can be dangerous- I've had an easier time regulating it with the protein on keto.It is shown that metformin can increase serotonin levels and thus regulate mood, but I think that one of the main reasons for positive effects on anxiety and mood is mainly to better regulation of insulin and glucose levels. Also, metformin will at least in first couple of weeks disrupt the way your digestive system works, and being that it is ...Reddit is a popular social media platform that has gained immense popularity over the years. With millions of active users, it is an excellent platform for promoting your website a...Oct 18, 2022 · Patients treated with metformin lost on average 10-14 pounds (5.6% to 6.5% of body weight) compared to controls who gained 6-8 pounds during the same time period. What’s interesting is that the percentage of weight loss achieved in each individual was independent of age, sex, or BMI. This means that if you are only 5-10 pounds overweight, it ... The tummy issues can vary if you have a generic form, from my experience. I found that out the not-so-fun way. When I first started Metformin (also for the damn PCOS), I lost about 15lbs, but that was it. Metformin tried to kill me via my liver/liver enzymes- my main symptoms were severe fatigue and feeling like I swallowed tacks for hours after each dose… progressed after only a week into thinking I had kidney stones coming on, only it was a significantly enlarged liver.Reddit, often referred to as the “front page of the internet,” is a powerful platform that can provide marketers with a wealth of opportunities to connect with their target audienc...That reason is likely b/c you have insulin resistance, which in turn is the underlying driver of the abnormal hormones that mess up cycling (in most cases of PCOS). Metformin helps treat the insulin resistance, which in turn helps normalize the abnormal hormones that cause the PCOS symptoms like abnormal cycling and lack of ovulation.Metformin during pregnancy impacts offspring brain development, finds study. by Deutsches Zentrum fuer Diabetesforschung DZD. Maternal HFD intake during …Type 2. I wanted to share my personal experience with Ozempic vs. Metformin to see if anyone else has similar results. For a couple of years I'd been taking Metformin and had good results. In particular, with regular exercise, normal weight, and fairly strict control of my diet, I had achieved an A1C level of 6.4 as of December 2022.For years mt HbA1c was ~ 7. My doc upped my metformin to 2G/daily. There was no change for 5 months then suddenly I lost 5 pounds ( I also changed my magnesium from citrate to gycinate) in one month without trying. I simply had no appetite. I cut back to 1500 mg metformin and the weight loss has continued about 1/4 pound/week.Metformin is a drug that is being studied for its potential to treat liver fibrosis, a condition where the liver becomes stiff and scarred. This study found that metformin affects the mitochondria (the powerhouses of cells) in a certain type of liver cell called hepatic stellate cells (HSCs) and helps to decrease the severity of liver fibrosis.Dec 10, 2566 BE ... I think the side effects of metformin are drastically overblown. A case of the minority of experiences having a very loud voice. Other than the ...Will say that Metformin can help you poop while on Mounjaro. So when you get off you can experience the constipation. Make sure you drink plenty of water when on both. Consider a high quality B complex supplement. If your hair starts falling out, get labs done to check for thiamine and folate, among others per your prescriber. r/Mounjaro_ForType2.Reddit is a popular social media platform that has gained immense popularity over the years. With millions of active users, it is an excellent platform for promoting your website a...Good sleep and regular exercise have worked better than anything else I've seen or tried. However, metformin is very safe. There's a reason it is first line treatment for T2DM. One should take it with meals to reduce the diarrhea effect it can have, but besides that it is relatively well tolerated.Reddit has raised a new funding round, totaling $250 million. This is the company’s Series E round of financing, and it comes hot on the heels of renewed public attention on the si...The studies he's done show that there are several things that have a significant impact on this kind of healthy longevity - including growth hormone, cholesterol, and mitochondrial peptides. He also suggests that metformin, a diabetes medication, could be a powerful tool for slowing down age-related decline.Alternatives to Reddit, Stumbleupon and Digg include sites like Slashdot, Delicious, Tumblr and 4chan, which provide access to user-generated content. These sites all offer their u... So, when my dad was diagnosed, he was put on metformin plain. He started having bowel problems like you. We didn't connect it to his medication for a long time. Fast forward 10 years. I'm diagnosed with T2. I start metformin plain, and the side effects don't go away. I mention it to my doctor, and he switched me to metformin ER. My side effects ... The root cause of PCOS is insulin resistance, so that needs to be treated by metformin/Berberine, moderate gentle exercise, and a whole foods diet. The pill can actually make it way worse because it actually causes IR! MysiVlooi • 3 yr. ago.Metformin Dosage for Weight Loss. How Effective Is Metformin? Is Metformin Better for Weight Loss Than Ozempic? Is Long-Term Weight Loss Possible …Metformin made me beyond exhausted. I’d sleep 16 hours a day and the rest of the time was too tired to get off the couch. All my hormone and vitamin levels were perfect, so no issue with low b12, low iron, low thyroid, etc. It was 100% the Metformin. Within 2 days of stopping all of my energy came back.Many pharmacies like Walgreens sell safe drug disposal bags - all that is involved is putting the med into the bag with some water and the chemical provided, and then it is safe to dispose. Another option if you can’t find one through your PD or pharmacy. • 4 yr. ago. Give them to the pharmacy, they have safe disposal methods.Is metformin actually good for my thyroid. I was prescribed metformin for my hashimoto's it's supposed to help with my fatigue and weight loss don't get me wrong it helps the fatigue and it kind of helps with weight loss but I've read some stuff about it being used to be treated for diabetes and the people who use metformin to treat their ...Good sleep and regular exercise have worked better than anything else I've seen or tried. However, metformin is very safe. There's a reason it is first line treatment for T2DM. One should take it with meals to reduce the diarrhea effect it can have, but besides that it is relatively well tolerated.I tell him about my stomach issues and he says its gastritis and then he says I’m pre-diabetic too. Long story short, he prescribed me with an antidepressant, sleeping aid, two gastritis pills, and metformin. The metformin tore threw me (tmi, sorry) to the point where the diarrhea was so frequent and so intense that I started to bleed a ...Reddit is a popular social media platform that has gained immense popularity over the years. With millions of active users, it is an excellent platform for promoting your website a...In the short and medium terms, Inositol has been found to be as effective as metformin (and in some studies more so) with less side effects. Not only does it help control blood sugar and reduce insulin resistance the way metformin does, it also helps reduce inflammation, lower cholesterol, improve egg quality, curb hunger and reduce sugar ...Using their understanding of clinical research, the authors recommended that the GLP-1 receptor agonists should be first-line therapy in type 2 diabetes. They invoke …After setting aside the feature as a paid perk, Reddit will now let just about everybody reply with a GIF. Starting today, any safe-for-work and non-quarantined subreddit can opt i...
Apr 14, 2565 BE ... Metformin and prediabetes · Your doctor will tell you if you need to increase the metformin. I was on 500mg of metformin for awhile and it was .... What to do when your bored with a friend
I have always had a fairly regulated appetite and am within a healthy BMI, but since my Dr put me on Metformin 6 weeks ago 2x 500mg, I've noticed quite a bit of weight gain in my legs and stomach and an increase in appetite overall : (. I was fine when it was 1x 500, but I have been gaining weight on the adjustment. Metformin is the first medication almost everyone is put on because both IR and XR are super cheap. (I'm pretty sure XR costs more, but when I say "more" it's not that much more and still super cheap and definitely going to be less expensive than almost every other option.) Meformin is on the $4 list here in the US, and when I …26. Sort by: Add a Comment. ProduceOk354. • 1 yr. ago. I would add acarbose, for the reason that it's actually been rigorously investigated as a combination treatment with rapamycin and shown to produce synergistic effects. Also, it has a plausible mechanism of action for extending lifespan, as opposed to metformin, which as far as I am aware ...Update: Got way worse this morning. Messaged the doc and he said to stop the glimepiride for now. New diagnosis, a little over a week in. My blood sugar is responding well to the metformin and glimepiride the doctor put me on, but I've noticed in the past couple days I've had a couple of 'black moods' - crying jags over silly things and the like - which usually …The fact that metformin and sprint exercise affect your body weight through the same pathway is both weird and interesting. Long and his colleagues also analyzed …Yes, it goes away almost completely. I’m on 2000 mg but it took almost a month to work up to that and a few month after that until the symptoms really eased up. Definitely go with the extended release formula and be patient. Good luck!! vivagypsy • 5 yr. ago. I had some GI upset last week which was week 1.Metformin is for high blood sugar which mk677 can cause, but this is how the drug works... increase of glucose to pump into the muscle to retain water and help build/recover. alongside the natty HGH pulses, mk677 is great drug. Thanks for the response! So I've actually ran MK multiple times and have had awesome results.I think this helped me get back into the habit of a full 7-8 hour night of sleep. I also started working out consistently shortly after this post. I would wake up early before work and get 30-45 min on my exercise bike. I think this helped to exhaust me physically. It might also be helpful to take your metformin earlier.For example, one could take metformin to moderate the BG numbers while continuing to eat carbs/sugar just worsening an insulin sensitivity problem and the descent into a worsening problem. Or one could take it along with proper diet and exercise to keep BG numbers very nice and low which probably at least increases the odds of not sliding further.Metformin made me beyond exhausted. I’d sleep 16 hours a day and the rest of the time was too tired to get off the couch. All my hormone and vitamin levels were perfect, so no issue with low b12, low iron, low thyroid, etc. It was 100% the Metformin. Within 2 days of stopping all of my energy came back.Metformin and stomach issues. Hey! I was recently diagnosed with DT2 with an A1c 9.7 😢 doctor prescribed 2 gr of metformin daily and advised me to start gradually and now I’m taking the two pills however is making me sick with diarrhea and nausea, I noticed this when I started to take the second pill. I also had IBS before so it’s …Oct 18, 2022 · Patients treated with metformin lost on average 10-14 pounds (5.6% to 6.5% of body weight) compared to controls who gained 6-8 pounds during the same time period. What’s interesting is that the percentage of weight loss achieved in each individual was independent of age, sex, or BMI. This means that if you are only 5-10 pounds overweight, it ... Apr 7, 2565 BE ... single. symptom., and the biggest being that it immediately fixed my amenorrhea. It lowered my sugar cravings (although the effect was stronger ...I am currently on 100mg of Topamax for migraine / weight loss prevention and 1000mg Metformin for Insulin resistant PCOS. So far, I have lost 15lbs with this combination! I actually haven’t been taking the full 1000mg. So I’ve just been doing 500mg for now. because I was worried about the rare side affect of lactic acidosis which I’ve ...26. Sort by: Add a Comment. ProduceOk354. • 1 yr. ago. I would add acarbose, for the reason that it's actually been rigorously investigated as a combination treatment with rapamycin and shown to produce synergistic effects. Also, it has a plausible mechanism of action for extending lifespan, as opposed to metformin, which as far as I am aware ...After-Swordfish-5603. •. I also just got prescribed topiramate and metformin as well! When I did weight loss meds before through my docs office, I was prescribed topiramate and phentermine and I lost 14lbs in a few months on both. However then I noticed the effects started to wear off and I was back to boredom eating.Reddit is not the only company launching ways for communities to host conversations. Reddit announced Thursday that it is testing Discord-like chat channels with select subreddits....The most common side effect of metformin use is gastrointestinal, i.e, heartburn, gas, nausea, diarrhea, which to me are potentially unpleasant enough to preclude its use as a "longevity" drug in otherwise healthy people w/ normal blood glucose function. Still, metformin is one of the safer drugs to take, much safer than OTC NSAIDs..